1+ day, 22+ hour ago   (371+ words) AstraZeneca’s experimental lung disease drug has significantly reduced COPD flare-ups in two late-stage trials, strengthening the case for a potential new biologic treatment for the condition. COPD is a progressive lung disease that causes breathing difficulties, coughing and excess mucus…...

3+ day, 22+ hour ago   (365+ words) The Phase IV, double-blind, randomised, placebo-controlled crossover trial provides new evidence on the cardiopulmonary effects of long-acting dual bronchodilation in a population in whom COPD and cardiac dysfunction coexist. Lung hyperinflation is common in COPD and can adversely affect cardiac…...

1+ week, 1+ day ago   (313+ words) ARTIFICIAL intelligence (AI) may help radiologists interpret chest X-rays faster and with greater confidence, but this does not necessarily translate into greater diagnostic accuracy, according to new research. A prospective study evaluating four commercially available AI systems found that AI…...

1+ week, 3+ day ago   (429+ words) EMJ This site is intended for healthcare professionals Brepocitinib in Dermatomyositis Delivers Significant Clinical Results - Brepocitinib 30 mg achieved a 15.3-point higher Total Improvement Score versus placebo at week 52. - Sixty-two percent of patients taking 30 mg tapered daily prednisone equivalents to 2.5 mg…...

2+ week, 3+ day ago   (409+ words) Patients with a rare and potentially life-threatening blood disorder now have an FDA-approved treatment for the first time. The US regulator has cleared Johnson & Johnson’s Imaavy (nipocalimab) for warm autoimmune haemolytic anaemia, or wAIHA, in patients aged 12 and older who…...

2+ week, 3+ day ago   (346+ words) A MULTICENTRE retrospective study of 685 patients with unresectable hepatocellular carcinoma (uHCC) found that progressive disease (PD) was the leading reason for discontinuation of atezolizumab plus bevacizumab, while older age and poorer liver function identified patients at greater risk of toxicity-related…...

2+ week, 4+ day ago   (169+ words) EMJ This site is intended for healthcare professionals TOURMALINE: Safety and Efficacy of Durvalumab in Combination with Gemcitabine-Based Chemotherapy in Advanced Biliary Tract Cancer This infographic and the studies discussed were funded by AstraZeneca. This content is intended for US…...

2+ week, 5+ day ago   (401+ words) GSK has received its first global approval for its chronic hepatitis B drug and key support for a potential rectal cancer therapy, it announced on Monday. The British pharmaceutical giant shared that bepirovirsen, to be branded as Hibsago, has been…...

3+ week, 3+ day ago   (295+ words) Amylyx Pharmaceuticals’ experimental drug reportedly reduced dangerous episodes of low blood sugar in patients who have undergone bariatric surgery, in a late-stage trial. Currently, there are no approved treatments for a condition known as post-bariatric hypoglycemia, which causes extreme blood…...

3+ week, 3+ day ago   (504+ words) A great therapy can clear every scientific hurdle and still fail to reach the patient. Often, the difference is friction: a series of small barriers that can have major consequences Words by Isabel O’Brien The alarm goes off at 6am. You…...